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Опис книги
Professional training of medical professionals of the general practicioners network is a very important task, since they are an important element in addressing the TB epidemic. Therefore there was a need for a national textbook of tuberculosis involving Ukrainian and foreign highly skilled professionals in this field, who have invaluable clinical, teaching and research experience. Textbook meets the requirements of the Bologna process. It provides information about the etiology, pathogenesis, clinical presentation, diagnosis, treatment and prevention of tuberculosis. Texbook expounds latest achievements of national and international scientists, WHO standardized protocols in compliance with consistency and volume of standard provision of specialized care for TB patients.
For students in higher education institutions.
Зміст книги
INTRODUCTION
KEY TERMS & ABBREVIATIONS
Chapter 1. GENERAL BASICS OF PHTHISIOLOGY
1.1. History of Phthisiology (V.I. Petrenko)
1.2. Basics of TB Control and Elimination (Pierpaolo di Colombani)
1.3. The Stop TB Strategy (Pierpaolo di Colombani)
1.3.1. TB Control and Styblo’s Model
1.3.2. The DOTS Strategy
1.3.3. The Stop TB Strategy
1.4. Epidemiology and Control of TB at the Global Level (Richard Zaleskis)
1.4.1. Basics of TB Epidemiology
1.4.2. TB Epidemiology in the World and in the European Region
1.4.3. Combating TB in the World and in the European Region
1.4.4. Achievements in TB Control
1.4.5. Main Challenges in TB Control
1.4.6. Next Steps in Global TB Control and its Eradication
1.5. TB Epidemiology and Control in Ukraine (O.S. Shevchenko)
1.5.1. TB Control in Ukraine
1.5.2. General Issues on TB Epidemiology
1.5.3. Epidemiology of TB in Ukraine
1.6. Prevention of TB (Giovanni Battista Migliori)
1.6.1. Social Determinants and Noncommunicable Diseases (Giovanni Battista Migliori)
1.6.2. Contact Tracing (Giovanni Battista Migliori)
1.6.3. BCG Vaccination (Giovanni Battista Migliori, Richard Zaleskis)
1.6.4. Psychological Aspects of Stigma and Discrimination of Patients with Tuberculosis and TB/HIV Coinfection (L.D. Todoriko)
1.7. Infection Control (S.M. Ljepshina)
1.7.1. Infection Control Rationale (Definition)
1.7.2. TB Infection Control in Healthcare Facilities
1.7.3. Administrative Control
1.7.4. Environmental Control/Control of Air Indoors
1.7.5. Personal Respiratory Protection
1.7.6. Infection Control in TB Patients’ Homes
Chapter 2. ETIOLOGY AND PATHOGENESIS OF TUBERCULOSIS
2.1. TB Etiology (V.I. Petrenko, O.S. Shevchenko)
2.1.1. Causative Agent of TB and Its Types
2.1.2. MTB Replication
2.1.3. MTB Structure
2.1.4. MTB Genetics
2.1.5. MTB Resistance to AntiTB Drugs
2.1.6. Environmental Stability of MTB
2.1.7. NonTuberculosis (Atypical) Mycobacteria
2.2. Pathogenesis of Tuberculosis (O.K. Asmolov, V.I. Petrenko)
2.2.1. Immunophysiology and Immunopathology of Tuberculosis
2.2.2. Pathophisiology of Tuberculosis
Chapter 3. DETECTION AND DIAGNOSIS OF TUBERCULOSIS
3.1. Case Finding, Diagnosis and Screening (Giovanni Battista Migliori)
3.1.1. Casefinding
3.1.2. Diagnosis
3.1.3. Screening
3.1.4. From Diagnosis to Registration
3.2. Practical Approach to Lung Health (PAL) (Giovanni Battista Migliori)
3.3. Methodology of TB Patient Observation
3.3.1. Case History (V.I. Petrenko)
3.3.2. Physical Examination (V.I. Petrenko)
3.3.3. Haematology (V.I. Petrenko)
3.3.4. Biochemistry (V.I. Petrenko)
3.3.5. Laboratory Testing for MTB (V.I. Petrenko, Richard Zaleskis)
3.3.6. The Role of Tuberculin Skin Test (Mantoux Test) in Diagnosis of TB (Giovanni Battista Migliori, V.I. Petrenko)
3.3.7. Other Immunology Testing for Tuberculosis in Ukraine (V.I. Petrenko)
3.3.8. Radiological Diagnosis (V.I. Petrenko)
3.3.9. Functional Tests (L.A. Gryschuk)
3.3.10. Instrumental Diagnostics (V.I. Petrenko)
Chapter 4. TREATMENT OF PATIENTS WITH TUBERCULOSIS
4.1. Brief Historical Overview of the Development of Antimycobacterial Therapy (Vaira Laimane)
4.2. Principles of Treatment of Patients with Tuberculosis (V.I. Petrenko)
4.3. Antimycobacterials. Theoretical Basis of Antituberculosis Treatment (V.I. Petrenko, Vaira Laimane)
4.3.1. Antituberculosis Drugs Activity
4.3.2. Bacteriologic Bases for TB Treatment (Vaira Laimane)
4.3.3. Antituberculosis Drugs (V.I. Petrenko, Richard Zaleskis)
4.3.4. Side Effects of AntiTB Drugs (B.M. Puchlykh)
4.4. Treatment of Susceptible TB (Vaira Laimane)
4.4.1. The Aims of Susceptible TB Treatment
4.4.2. Standardized Treatment Regimens for Active Tuberculosis in Defined Patient Groups (L.D. Todorico)
4.4.3. Phases of Treatment of Pulmonary and Extra Pulmonary Tuberculosis
4.4.4. Evidence Based Recommendations