Biological Chemistry=Біологічна хімія. — 3-тє вид. Рекомендовано вченою радою Тернопільського державного медичного університету ім. І.Горбачевського як підручник для студентів медичних і фармацевтичних факультетів вищих навчальних закладів України.
ISBN: 978-966-382-835-0
Автор: Губський Ю.І. та ін.
Рік: 2020
Мова: англійська
Сторінок: 488
Обкладинка: тверда
Ціна: 390 грн.

The textbook in Biological Chemistry consists of 30 chapters made up of text material and plentiful illustrations, including chemical formulas, reaction equations, drawings depicting complicated intracellular transformations of biomolecules, and metabolic “charts”.
The textbook is intended for students of medical and pharmaceutical faculties of higher educational establishments of Ukraine.

Підручник з біологічної хімії складається з 30 розділів і містить текстові матеріали та велику кількість ілюстрацій, у тому числі хімічні формули, реакції та їх рівняння, рисунки складних внутрішньоклітинних перетворень біомолекул і метаболічні “схеми”. Підручник призначений для студентів медичних та фармацевтичних факультетів вищих навчальних закладів України.

PREFACE ......10
Part 1. BIOMOLECULES. CELLS. METABOLISM
Chapter 1. BIOCHEMISTRY: BIOMOLECULES, METABOLISM.. 13
1.1. Biochemistry as fundamental biomedical science... 13
1.2. Biomolecules – major classes, representatives .... 14
Chapter 2. PROTEINS. AMINO ACIDS. PEPTIDES.... 19
2.1. Amino acids: structure, properties.... 19
2.2. Peptide bonds, polypeptides ....24
2.3. Proteins. Levels of protein structure ...28
Chapter 3. NUCLEIC ACIDS. NUCLEOTIDES. DNA. RNA ..36
3.1. Nucleic acids and the flow of genetic information ...36
3.2. Nucleotides: structure, biological functions .. 37
3.3. Nucleic acids as polynucleotides: DNA, RNA ....42
Chapter 4. CARBOHYDRATES. SUGARS AND THEIR DERIVATIVES....46
4.1. Monosaccharides. Hexoses. Pentoses. Amino sugars .. 47
4.2. Oligosaccharides. Homopolysaccharides .....49
4.3. Heteropolysaccharides. Glycoproteins ..... 53
Chapter 5. LIPIDS. FATTY ACIDS. BIOMEMBRANES ..... 57
5.1. General characteristics of lipids. Biological functions ...... 57
5.2. Fatty acids: structure and properties .... 58
5.3. Structure and properties of special classes of lipids ... 61
5.4. Steroids: cholesterol, bile acids, steroid hormones .... 67
Chapter 6. CELLS. METABOLISM: GENERAL ASPECTS ... 71
6.1. Metabolism: overall conception, metabolic pathways ... 71
6.2. Cells. Compartmentalization of metabolic pathways.... 72
Part 2. ENZYMES. GENERAL METABOLIC PATHWAYS
Chapter 7. METABOLISM. ENZYMATIC REACTIONS ..... 77
7.1. Metabolism: general conceptions, metabolic pathways ... 77
7.2. Enzymes as the principal molecular devices of metabolism ...80
7.3. Enzyme nomenclature and classification ...84
7.4. Molecular mechanisms of enzyme catalysis ... 91
Chapter 8. COENZYMES. CONTROL OF ENZYMATIC REACTIONS ...94
8.1. Coenzymes: classification, structure. Vitamins as coenzyme precursors ....94
8.2. Kinetics of enzyme catalysis. Michaelis – Menten theory...99
8.3. Inhibition of enzymes. Kinds of inhibitors ....103
8.4. Enzymic catalysis regulatory mechanisms .... 107
Chapter 9. BIOENERGETICS-1. CATABOLIC PATHWAYS.TRICARBOXYLIC ACID CYCLE ... 114
9.1. Bioenergetics. ATP and other high-energy compounds . 114
9.2. Overview of catabolic pathway steps ... 116
9.3. Tricarboxylic acid cycle: overview .... 117
9.4. Tricarboxylic acid cycle: reactions and enzymes ... 118
Chapter 10. BIOENERGETICS-2. MITOCHONDRIAL ELECTRON TRANSPORT. OXIDATIVE PHOSPHORYLATION .... 124
10.1. General notions of free energy transfer in biochemical systems .. 124
10.2. Electron transport chain in mitochondria ...126
10.3. Oxidative phosphorylation. ATP synthase ...131
Part 3. METABOLISM OF MAJOR CLASSES OF BIOMOLECULES
Chapter 11. CARBOHYDRATE METABOLISM-1. PATHWAYS OF GLUCOSE OXIDATION ... 137
11.1. Major routes of carbohydrate metabolism... 137
11.2. Aerobic and anaerobic oxidation of glucose. Glycolysis .... 139
11.3. Enzymatic reactions of glycolysis. Regulation of glycolysis ..140
11.4. Aerobic oxidation of glucose. Oxidative decarboxylation of pyruvate.....149
11.5. Pentose phosphate pathway .....150
Chapter 12. CARBOHYDRATE METABOLISM-2. GLYCOGEN METABOLISM.
GLUCONEOGENESIS..... 156
12.1. Glycogen metabolism. Glycogen-storage diseases .. 156
12.2. Gluconeogenesis: reactions, regulation.... 167
12.3. Regulation of carbohydrate metabolism . . . . 172
12.4. Control of blood plasma glucose. Diabetes mellitus... 174
Chapter 13. LIPID METABOLISM-1. TRIACYLGLYCEROL CATABOLISM. OXIDATION OF FATTY ACIDS. KETOGENESIS .... 177
13.1. Lipids: general characteristics, biological functions . 177
13.2. Fat metabolism: overview, lipolysis ..... 179
13.3. Degradation of fatty acids (?-oxidation) ...... 182
13.4. Ketone bodies. Ketogenesis in diabetes mellitus .... 188
Chapter 14. LIPID METABOLISM-2. LIPOGENESIS. CHOLESTEROL METABOLISM. LIPID METABOLISM PATHOLOGY .193
14.1. Biosynthesis of fatty acids: reactions, enzymes .... 193
14.2. Biosynthesis of acylglycerols: triglycerides, phosphoglycerides... 197
14.3